Ibuprofen is a chemical compound also known as propanoic acid, which is used mainly to reduce fever (antipyretic properties), relieve headache, dental, muscular, post-surgical, mild neurological pain and menstrual cramps, in addition to progressively decreasing inflammation in muscular areas. In certain cases, it can be of great help in treating acne, even being available topically for better effect.
The maximum recommended dose for adults is 1200 mg daily; Under the supervision of a doctor, this can be increased to 800 mg / dose, that is, 3200 mg daily. In children, the established amount ranges from 5 to 10 mg per kg, with 30 mg / kg becoming the maximum amount that can be administered, following an estimated time interval of 6 or 8 hours. The current presentation is oral; According to research, the absorption rate of the drug is medium, making it slower with food intake or, on the contrary, accelerating with the action of L-arginine.
A research division, belonging to the Boots Group, discovered this compound during the 1960s. Stewart Adams, John Nicholson, Jeff Bruce Wilson, Andrew Dunlop and Colin Burrows were the doctors in charge of the project.
It was initially developed for the purpose of relieving the symptoms that accompany rheumatoid arthritis, but it was quite helpful for other pain that does not occur from this disease. The Dr.Adams was the first person in history to test the effects of this potent drug with a hangover. Its commercialization began in 1969 in the United Kingdom and in 1974 in the United States, to later expand on a global scale. The World Health Organization (WHO) includes it in the list of essential drugs.
Despite all the benefits that ibuprofen brings, it can also cause a series of adverse reactions, which are considered a great risk to the body; the most common signs of this happening are: rash, swelling in various areas of the body, shortness of breath, rapid heartbeat, aggression and confusion. In addition to this, some cases of overdose have been found, a product of the uncontrolled consumption of the drug, since no prescription is needed to get it. Most of the patients had seizures, internal effusions, and tachycardia, while others went into a coma or died.
